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Portland Mews is a cobbled mews on the south side of Berwick Street's neighbour D'Arblay Street, set between Berwick Street and Poland Street in central Soho. D'Arblay Street was laid out in 1735 as Portland Street, on land owned by the Dukes of Portland and once known as Doghouse Close, before being renamed after Frances Burney, Madame d'Arblay.
The mews keeps the Portland name from that earlier street. Its buildings, with exposed brickwork, stripped floors and original flagstone entrances, are now mostly small offices and commercial studios, a typical Soho mews given over to working space rather than shopfronts.